Hydrogen technologies improve the integration of fluctuating renewable electricity into the energy system, promote sector coupling and open up new paths to sustainable production routes for the manufacturing industry. This applies both to large-scale industrial projects and overarching infrastructure developments as well as to projects at regional level – for example in industrial estates, at logistics locations such as ports or in municipalities and, under certain conditions, also in residential areas. But which technologies are best used in which scenario? What infrastructural requirements need to be created? How can regionally available resources such as water be used responsibly? How can the interests of stakeholders and actors from the surrounding area be integrated in the best possible way? And what options are there for the sensible use of hydrogen and the by-products of its production: oxygen and heat?